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REMEDY : BNSSG referral pathways & Joint Formulary

BNSSG Adult Joint Formulary

17. Miscellaneous Preparations

First line drugs Second line drugs Specialist drugs Secondary care drugs
Recommended in both primary and secondary care Alternatives (often in specific conditions) in both primary and secondary care Where a specialist input is needed (see introduction for definition) Prescribing principally within secondary care only

Miscellaneous Preparations

This page is for medicinal products that have been through the Joint Formulary Process, and therefore are Formulary within BNSSG, however they are not listed within the BNF. 


All are TLS Red

Acid Citrate Dextrose

  • 500ml bags for use with Cell Saver machine

  • UHB only 

Bone Morphogenetic Protein

  • Inductos®

  • Osigraft®

  • NB Not for Complex spinal surgery - NHS England is the commissioner for this indication and they are not routinely commissioned.  An IFR application is required.

Eleview lifting solution

  • Lifting solution for endoscopic submucosal dissection (ESD) of polyps


  • Surgical glue

Lutetium (177Lu) oxodotreotide

  • As per NICE TA 541 for treating unresectable or metastatic neuroendocrine tumours

Methoxsalen (Uvadex®)

  • For use in by the Bristol Therapeutic Aphoresis Unit for Photophoresis. 

Regadenoson (Rapiscan®)

  • For use as a pharmacological stress agent for radionuclide myocardial perfusion imaging (MPI) in adult patients unable to undergo adequate exercise stress.


  • For use in Echocardiography, in patients with suspected or established cardiovascular disease to provide opacification of cardiac chambers and enhance left ventricular endocardial border delineation. 

  • SonoVue should only be used in patients where study without contrast enhancement is inconclusive

Autologous chondrocyte implantation

  • As per NICE TA477 Autologous chondrocyte implantation for treating symptomatic articular cartilage defects of the knee

  • As per NICE TA508  Autologus chondrocyte implantation using chondrosphere for treating symptomatic articular cartilage defects of the knee